Photothermal Cancer Treatments: Next Gen Care

Dr. Anatoliy Pinchuck, 2025 Fellowship Cohort

Research Summary

This project is advancing a next-generation cancer treatment approach that combines infrared light technology with engineered gold nanoparticle-dye conjugates to create a more targeted, minimally invasive alternative to conventional cancer therapies. In collaboration with Colorado Springs startup Lahjavida, the research focuses on optimizing photothermal treatment methods that selectively target cancer cells while minimizing damage to healthy tissue.

By integrating nanotechnology, biochemistry, and applied physics, the project bridges fundamental scientific discovery with real-world biomedical applications. The work also creates a collaborative research environment where undergraduate and graduate students gain hands-on experience in emerging medical technologies, translational research, and interdisciplinary 


The Problem: Current cancer treatment methods are often invasive, physically taxing, and associated with significant side effects that can negatively impact patient quality of life. Existing therapies may also struggle to precisely target cancer cells without damaging surrounding healthy tissue, creating a need for safer, more effective treatment strategies. 

The Innovation: This project develops a novel photothermal cancer treatment platform that uses infrared lasers or LED light sources combined with gold nanoparticle-dye conjugates to selectively target and destroy cancer cells. By maximizing light-to-heat conversion efficiency and improving active tumor targeting, the technology aims to create a more precise, less invasive, and potentially more effective cancer treatment approach.

Community and Industry Impact

This project contributes to the broader healthcare and scientific community by advancing research that could improve cancer treatment outcomes while reducing the physical burden on patients. Through its partnership with Lahjavida, the initiative also strengthens connections between university research and the regional biotechnology sector, supporting innovation-driven economic and healthcare development in Colorado Springs. 

Student Engagement and Mentorship

The project creates extensive opportunities for undergraduate and graduate student involvement in nanotechnology, biochemistry, cell biology, and biomedical research. Students gain hands-on experience working on cutting-edge scientific applications while developing skills in interdisciplinary collaboration, laboratory research, and translational innovation that prepare them for careers in biotechnology and medicine.

Increasing UCCS Visibility

By combining university research with startup collaboration, the project positions UCCS as a leader in applied nanotechnology and biomedical innovation. The research has the potential to generate peer-reviewed publications, patents, and commercialization opportunities that elevate the university’s visibility within scientific, medical, and entrepreneurial communities. 

Timeline

PROJECT DELIVERABLES

  • Laboratory photothermal treatment testing protocols
  • Infrared laser and LED treatment optimization
  • Cancer cell targeting and efficacy data
  • Undergraduate and graduate student research training
  • Industry collaboration with Lahjavida
  • Conference presentations and research publications

Summer Development

MAY - AUGUST 2026

  • Train undergraduate and graduate researchers in nanoparticle synthesis, instrumentation and experimental techniques.
  • Continue collaborative development with Lahjavida to align laboratory research with clinical translation goals.

Research Expansion

SEPTEMBER 2026 - MAY 2027

  • Refine photothermal treatment platform based on experimental results.
  • Prepare manuscripts, conference presentations and external funding proposals.
  • Document student research outcomes and interdisciplinary training experiences.

Meet the Innovator

Dr. Pinchuk headshot

Professional Bio

Anatoliy Pinchuk is a Professor of Physics and Energy Science at the University of Colorado Colorado Springs (UCCS). His research focuses on nanotechnology, plasmonics and photothermal therapies, with an emphasis on developing innovative biomedical applications that translate fundamental physics into real-world medical solutions. His current work explores infrared light and engineered gold nanoparticle-dye conjugates as a targeted, minimally invasive approach to cancer treatment through a collaboration with Colorado Springs startup Lahjavida.

Pinchuk earned his Ph.D. in Physics from the National Academy of Sciences of Ukraine and completed postdoctoral fellowships at RWTH Aachen University as a Humboldt Fellow and at Northwestern University. Since joining UCCS in 2008, he has built an internationally recognized research program in nanophotonics and biomedical optics, authoring more than 70 peer-reviewed publications, earning multiple U.S. patents and receiving the University of Colorado Faculty Award for Excellence in Research and the University's New Inventor of the Year Award. Through his research and mentorship, he prepares undergraduate and graduate students to advance innovations in nanotechnology, biomedical research and translational science.

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